To me they are two different drugs with two different effects. in my opinion,valium(diazepam) is a very good med for mildly keeping your anxiety at bay for longer periods of timeit has a VERY LONG half life. clonazepam(klonopin) has the same feel except its a tiny bit more potent but still is excellent for keep.
Diazipam and clonazepam yes are both drugs that belong to the benzodiazapines group of drugs however clonazepam is used more as an anti convolsant in epilepsy when used in anxiety long term use is not recommended due to tolerance build up as 2mg clonazepam = 40mg diazepam.
Finally I found success with clonazepam and diazepam.
Clonazepam is stronger than diazepam but it has a shorter half-life. Clonazepam has a half-life ranging from 18-50 hours and diazepam's half-life ranges from 20-100 hours. So, on average, clonazepam leaves the body in half the time that diazepam does. This means that clonazepam has to be taken more frequently than.
Clonazepam has a half-life ranging from 18-50 hours and diazepam's half-life ranges from 20-100 hours. So, on average, clonazepam leaves the body in half the time that diazepam does. stoneMason Post 2 @fBoyle-- Clonazepam is stronger than diazepam. Clonazepam is stronger than diazepam but it has a shorter half-life. I suppose we could say that clonazepam is better for short term, more severe anxiety issues, in comparison to diazepam. Plus, everyone reacts to drugs differently. This means that clonazepam has to be taken more frequently than diazepam.
Parent (hrs). Half-life metabolite (hrs). Comparative Oral Dose. Long Acting. Chlordiazepoxide (Librium), Int. (po), 2-4(po), 5-30, 3-100, 10 mg. Diazepam1 Clonazepam1 (Rivotril), Int. 1-4, 18-39, -, 0.25mg. Lorazepam1 (Ativan). Int. (po), Rapid (sl, IV). 1-1.5 (po), 10-20, -, 1mg. Oxazepam1 (Serax), Slow, 2-3, 3-21.
0.7-1.6 6-20 - 0.5mg Clonazepam1 (Rivotril) Int. (po), Rapid (sl, IV) 1-1.5 (po) 10-20 - 1mg Oxazepam1 (Serax) Slow 2-3 3-21 - 15mg Temazepam1 (Restoril) Slow 0.75-1.5 10-20 - 30mg Short Acting Midazolam1 (Versed) Most Rapid IV 0.5-1 (IV ) 1-4 - - Triazolam (Halcion) Int. 1-4 18-39 - 0.25mg Lorazepam1 (Ativan) Int. (po) 2-4(po) 5-30 3-100 10 mg Diazepam1 (Valium) Rapid (po, IV) 1(po) 20-50 3-100 5 mg Flurazepam (Dalmane) Rapid 0.5-2 inactive 47-100 30 mg Intermediate Acting Alprazolam1 (Xanax) Int. Half-life metabolite (hrs) Comparative Oral Dose Long Acting Chlordiazepoxide (Librium) Int. 0.75-2 1.6-5.5 - 0.5mg 1 formulary drug 2 Rapid onset = within 15 minutes, Intermediate = 15-30 minutes, Slow = 30-60 minutes.
Table of Contents COMPARISON OF BENZODIAZEPINES.
Alprazolam (Xanax), chlordiazepoxide (Librium), chlorazepate (Tranxene), diazepam (Valium), lorazepam (Ativan), and midazolam are used for anxiety disorders. Clonazepam (Klonopin), clorazepate (Tranxene), lorazepam (Ativan), clobazam (Onfi), and diazepam (Valium) are used for seizure disorders.
Gbemudu received her B.S. in Biochemistry from Nova Southeastern University, her PharmD degree from University of Maryland, and MBA degree from University of Baltimore. She completed a one year post-doctoral fellowship with Rutgers University and Bristol Myers Squibb. Dr.
Although most benzodiazepines are used interchangeably, some are most commonly used for certain conditions.
Benzodiazepines differ in how quickly they start working, how long they continue to work, and for what they are most commonly prescribed.
Are there differences between benzodiazepines?
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He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles. Jay W. Marks, MD, is a board-certified internist and gastroenterologist.
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Metabolized by CYP2C19 and CYP3A4 to an active metabolite desmethyldiazepam. Diazepam and its metabolites are excreted mainly in the urine, principally as their glucuronide conjugates. Rapid onset of action, 1-5 min. Both benzodiazepines are highly lipid-soluble and penetrate rapidly into the brain.
Comparison chart:. Both clonazepam and diazepam are long-acting benzodiazepines. Two benzodiazepines differ in their effects on GABA-A receptors, route of metabolism, and elimination half-life.
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Published: December 02, 2016 Last updated: May 15, 2017.
Further reading References. Clonazepam is superior to diazepam in suppressing focal seizures and focal spiking 4.