Benzodiazepines are widely prescribed, with four of them—alprazolam (Xanax), clonazepam (Klonopin), diazepam (Valium) and lorazepam. therapeutic dosages of benzodiazepines are mainly anxiety symptoms.1,21 In addition, autonomic instability (i.e., increased heart rate and blood pressure level.
Benzodiazepines enhance the affinity of the recognition site for GABA by inducing conformational changes that make GABA binding more efficacious. Benzodiazepine receptors are linked predominantly to γ amino butyric acid (GABA) receptors, which sensitize benzodiazepine receptors to the neurotransmitter GABA, the most prominent inhibitory neurotransmitter in the central nervous system. Benzodiazepine receptors are ubiquitous throughout the central nervous system. 6. Activation of the benzodiazepine-GABA-chloride ionophor complex is responsible for producing the therapeutic anxiolytic effects of benzodiazepines and for mediating many of the side effects and, possibly, dependence and withdrawal from these drugs.
Detoxification from alcohol and other substances.
Some people abuse Klonopin because it can produce hallucinatory effects when taken in large enough doses. However, large doses of Klonopin can put users at risk of overdose. Klonopin is a central nervous system (CNS) depressant. As the drug slows the central nervous system, functions like heart rate.
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This causes a short, euphoric “high” followed by a hazy, intoxicated stupor. Some people crush Klonopin tablets up into a fine powder and snort them to intensify the drug’s effects. At higher than prescribed doses, Klonopin greatly depresses the central nervous system.
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Others may take alcohol to enhance Klonopin’s calming effects, whether it’s for the sake of trying to sleep or get a better high.
Scientific literature suggests the effects of snorting Clonazepam are similar to the effects of snorting other Benzodiazepines, such as Xanax. While snorting allows the user to quickly obtain the drug's relaxation and entrancing effects, serious symptoms can occur, such as: Slowed heart rate; Cessation of breathing; Erosion of.
Clonazepam may cause a variety of side effects, many of which can be dangerous if someone is abusing the drug. In fact, the Substance Abuse and Mental Health Services Administration states a 2006 study showed over 33,000 trips to the emergency room because of nonmedical use of the drug. Let’s take a closer look at the short and long term effects of this medication.
Clonazepam acts rather quickly when taken and produces a calming effect on the body. Because of this drug’s speed and efficiency, it is commonly combined with other illegal or prescription drugs and alcohol.
Heart monitor Benzodiazepines include Valium, Xanax, and Klonopin. These and other drugs in the class are sedatives. They slow down heart and breath rate. If you take too much of a benzodiazepine, you risk slowing your heart rate to damaging or fatal levels. You may develop blood clots that cause immediate or future.
The report continued, saying “Middle-aged adults who use recreational amphetamines…may develop a prematurely aging heart and experience health problems normally associated with older people.”2 Amphetamine users have a circulatory system that functions like that of someone much older. Stimulants affect the heart. A recent FOX News report explains that amphetamines, “have long been linked to heart attack, stroke, artery wall damage, bleeding in the brain, abnormal heart rhythm and sudden cardiac death.”2 Stimulant use can be fatal.
Combining Adderall and Klonopin may adversely affect the heart by sending it mixed signals. Adderall promotes the release of norepinephrine, which may increase heart rate, heart contractility and blood pressure. Conversely, the benzodiazepine Klonopin may oppose these cardiovascular effects.
Klonopin is actually a poor choice for this purpose. Other short-acting benzodiazepines are more useful for the purpose of coping with a psychostimulant crash, such as xanax, though the short-acting variety have considerably more abuse potential than comparable long-acting benzodiazepines. Due to its very long half life (~35 hours), ingesting Klonopin in the evening will almost certainly result in a multi-day hangover in subjects who are benzodiazepine-naive.
Klonopin (clonazepam) is a benzodiazepine drug which activates gamma-amino-butyric acid (GABA) A receptors in the brain, decreasing neuronal excitability.